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AZD1480

A potent JAK1 and JAK2 inhibitor
Catalog #: 2315
SKU-Size Size Price Qty
2315-1 1 mg
$55.00
2315-5 5 mg
$195.00
More Sizes Get Quote

Product Details

Alternate Name (S)-5-chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Appearance White to off-white solid
CAS # 935666-88-9
Molecular Formula C₁₄H₁₄ClFN₈
Molecular Weight 348.77
Purity ≥98% by HPLC
Solubility DMSO (~70 mg/ml) or Ethanol (~ 5 mg/ml)
SMILES CC1=CC(=NN1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=N3)F
InChi InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)/t8-/m0/s1
InChi Key PDOQBOJDRPLBQU-QMMMGPOBSA-N
PubChem CID 16659841
MDL Number MFCD16038904
Handling Protect from air and light
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AZD1480 is a novel ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ of 1.3 nM and 0.26 nM, respectively.


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