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AZD-5904

A potent myeloperoxidase (MPO) Inhibitor
Catalog #: B2598
SKU-Size Size Price Qty
B2598-5 5 mg
$175.00
B2598-25 25 mg
$695.00
More Sizes Get Quote

Product Details

Alternate Name AZ1, (S)-3-((tetrahydrofuran-2-yl)methyl)-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one, TX4, AZD5904
Peptide Sequence N/A
Appearance Beige to light yellow solid
CAS # 618913-30-7
Molecular Formula C₁₀H₁₂N₄O₂S
Molecular Weight 252.29
Purity ≥98% by HPLC
Solubility >100 mg/ml in DMSO
SMILES O=C1NC(N(C[[email protected]]2OCCC2)C3=C1NC=N3)=S
InChi InChI=1S/C10H12N4O2S/c15-9-7-8(12-5-11-7)14(10(17)13-9)4-6-2-1-3-16-6/h5-6H,1-4H2,(H,11,12)(H,13,15,17)/t6-/m0/s1
InChi Key RSPDBEVKURKEII-LURJTMIESA-N
PubChem CID 10264211
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AZD-5904 is a potent and irreversible inhibitor of human myeloperoxidase (MPO) (IC₅₀ = 140 nM). Displays similar potency in mouse and rat enzymes.


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