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AZD-5363

A potent pan-AKT kinase inhibitor
Catalog #: B1762

In stock

SKU-Size Size Price Qty
B1762-5 5 mg
$125.00
B1762-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name AZD-5363; AZD 5363; AZD5363; Capivasertib; (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide; 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Appearance Solid
CAS # 1143532-39-1
Molecular Formula C₂₁H₂₅ClN₆O₂
Molecular Weight 428.92
Purity >98%
Solubility DMSO
SMILES C1CN(CCC1(C(=O)NC(CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4
InChi InChI=1S/C21H25ClN6O2/c22-15-3-1-14(2-4-15)17(6-12-29)27-20(30)21(23)7-10-28(11-8-21)19-16-5-9-24-18(16)25-13-26-19/h1-5,9,13,17,29H,6-8,10-12,23H2,(H,27,30)(H,24,25,26)/t17-/m0/s1
InChi Key JDUBGYFRJFOXQC-KRWDZBQOSA-N
PubChem CID 25227436
MDL Number MFCD22628785
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AZD5363, also known as Capivasertib, is a potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.


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