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AZD-0156

A potent Ataxia Telangiectasia Mutated (ATM) kinase inhibitor
Catalog #: B1305
SKU-Size Size Price Qty
B1305-5 5 mg
$115.00
B1305-25 25 mg
$425.00
More Sizes Get Quote

Product Details

Alternate Name 8-[6-[3-(dimethylamino)propoxy]-3-pyridyl]-3-methyl-1-tetrahydropyran-4-yl-imidazo[4,5-c]quinolin-2-one
Appearance Crystalline solid
CAS # 1821428-35-6
Molecular Formula C₂₆H₃₁N₅O₃
Molecular Weight 461.57
Purity ≥98% by HPLC
Solubility DMSO
SMILES O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3
InChi InChI=1S/C26H31N5O3/c1-29(2)11-4-12-34-24-8-6-19(16-28-24)18-5-7-22-21(15-18)25-23(17-27-22)30(3)26(32)31(25)20-9-13-33-14-10-20/h5-8,15-17,20H,4,9-14H2,1-3H3
InChi Key AOTRIQLYUAFVSC-UHFFFAOYSA-N
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AZD-0156 is an orally bioavailable Ataxia Telangiectasia Mutated (ATM) kinase inhibitor, with potential chemo-/radio-sensitizing and antineoplastic activities. AZD-0156 targets and binds to ATM, thereby inhibiting the kinase activity of ATM and ATM-mediated signaling.


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