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AZ-7371

A non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1)
Catalog #: B2294

In stock

SKU-Size Size Price Qty
B2294-5 5 mg
$145.00
B2294-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name N-(2-hydroxyethyl)-1-((6-methoxy-5-methylpyrimidin-4-yl)methyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide; DprE1-IN-1
Appearance Crystalline solid
CAS # 1494675-86-3
Molecular Formula C₁₈H₂₁N₅O₃
Molecular Weight 355.40
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC1=CC2=C(C(=CN2CC3=C(C(=NC=N3)OC)C)C(=O)NCCO)N=C1
InChi InChI=1S/C18H21N5O3/c1-11-6-15-16(20-7-11)13(17(25)19-4-5-24)8-23(15)9-14-12(2)18(26-3)22-10-21-14/h6-8,10,24H,4-5,9H2,1-3H3,(H,19,25)
InChi Key VDRYGTNDKXIPSK-UHFFFAOYSA-N
PubChem CID 72792692
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

AZ-7371 is a non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with an IC₅₀ value of 10 nM. It also inhibits PDE6 (IC₅₀ = 4 µM).


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