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A potent inosine 5-monophosphate dehydrogenase (IMPDH) inhibitor
Catalog #: B2230
SKU-Size Size Price Qty
B2230-5 5 mg
B2230-25 25 mg
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Product Details

Alternate Name (R)-1-cyanobutan-2-yl ((S)-1-(3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)phenyl)ethyl)carbamate; VX-944
Appearance Crystalline solid
CAS # 297730-17-7
Molecular Formula C₂₅H₂₇N₅O₅
Molecular Weight 477.51
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C25H27N5O5/c1-4-20(10-11-26)35-25(32)28-16(2)17-6-5-7-18(12-17)29-24(31)30-19-8-9-21(22(13-19)33-3)23-14-27-15-34-23/h5-9,12-16,20H,4,10H2,1-3H3,(H,28,32)(H2,29,30,31)/t16-,20+/m0/s1
PubChem CID 9918559
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


AVN-944 is a potent inosine 5-monophosphate dehydrogenase (IMPDH) inhibitor that displays anticancer activities. AVN-944 inhibits the growth of human prostate cancer cells by inducing cell cycle arrest, cell death as well as differentiation.

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