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Aurintricarboxylic acid

A DNA topoisomerase II inhibitor
Catalog #: 1506
$80.00

Product Details

Cat # +Size 1506-1000
Size 1 g
Alternate Name ATA
Appearance Red-brown solid
CAS # 4431-00-9
Molecular Formula C₂₂H₁₄O₉
Molecular Weight 422.4
Purity >85%
Solubility 1 M NH₄OH (10 mg/ml)
SMILES C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)O)C(=O)O)C(=O)O)O
InChi InChI=1S/C22H14O9/c23-16-4-1-10(7-13(16)20(26)27)19(11-2-5-17(24)14(8-11)21(28)29)12-3-6-18(25)15(9-12)22(30)31/h1-9,23-24H,(H,26,27)(H,28,29)(H,30,31)
InChi Key GIXWDMTZECRIJT-UHFFFAOYSA-N
PubChem CID 2259
MDL Number MFCD00011663
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Inhibits apoptosis in various cell types induced by a variety of factors. Potent inhibitor of DNA topoisomerase II in vitro and protein-nucleic acid interactions. Stimulates the tyrosine phosphorylation of MAP kinases. Inhibits major calpain isoforms.


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