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A potent, and ATP-competitive inhibitor of ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase)
Catalog #: B1296
SKU-Size Size Price Qty
B1296-5 5 mg
B1296-25 25 mg
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Product Details

Alternate Name 2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine
Appearance Crystalline solid
CAS # 1097917-15-1
Molecular Formula C₂₉H₄₀N₈O₃S
Molecular Weight 580.74
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C29H40N8O3S/c1-21(2)41(38,39)27-8-6-5-7-25(27)33-29-31-20-30-28(34-29)32-24-10-9-23(19-26(24)40-4)36-13-11-22(12-14-36)37-17-15-35(3)16-18-37/h5-10,19-22H,11-18H2,1-4H3,(H2,30,31,32,33,34)
PubChem CID 25134326
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


ASP-3026 is a potent, and ATP-competitive inhibitor of ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase) with IC₅₀ value of 3.5 nM. It also inhibits ROS (IC₅₀ = 8.9 nM) and ACK (IC₅₀ = 5.8 nM). ASP3026 has been shown to overcome Crizotinib (Cat. No. 1934) resistance in non-small cell lung cancer.

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