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Aripiprazole

A high affinity dopamine D2 and 5-HT1A receptor partial agonist
Catalog #: B1186

In stock

SKU-Size Size Price Qty
B1186-10 10 mg
$65.00
B1186-50 50 mg
$195.00
More Sizes Get Quote

Product Details

Alternate Name 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
Appearance White solid
CAS # 129722-12-9
Molecular Formula C₂₃H₂₇Cl₂N₃O₂
Molecular Weight 448.4
Purity ≥98% by HPLC
Solubility DMSO (~30 mg/ml)
SMILES C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
InChi InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)
InChi Key CEUORZQYGODEFX-UHFFFAOYSA-N
PubChem CID 60795
MDL Number MFCD00892072
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Aripiprazole is a high affinity dopamine D2 and 5-HT1A receptor partial agonist (Ki values are ~1.64 and 5.59 nM respectively). Also 5-HT2A antagonist (Ki = 8.7 nM). Aripiprazole is a clinically useful neuroleptic and antipsychotic agent. It improves symptoms of psychosis associated with Alzheimer's disease. Aripiprazole blocks cocaine-seeking behavior without affecting other rewarding behaviors in animal models.


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