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Arcyriaflavin A

An inhibitor of CDK4 and CaMKII
Catalog #: B2902
SKU-Size Size Price Qty
B2902-1 1 mg
B2902-5 5 mg
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Product Details

Alternate Name 12,13-Dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione; 6,7,12,13-Tetrahydro-5,7-dioxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole
Appearance A crystalline solid
CAS # 118458-54-1
Molecular Formula C₂₀H₁₁N₃O₂
Molecular Weight 325.32
Purity ≥95%
Solubility ~1 mg/ml in DMSO
~5 mg/ml in DMF
InChi InChI=1S/C20H11N3O2/c24-19-15-13-9-5-1-3-7-11(9)21-17(13)18-14(16(15)20(25)23-19)10-6-2-4-8-12(10)22-18/h1-8,21-22H,(H,23,24,25)
PubChem CID 5327723
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Arcyriaflavin A inhibits cyclin-dependent kinase 4 (CDK4) with an IC₅₀ of 140 nM. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with an IC₅₀ of 25 nM. It inhibits the replication of human cytomegalovirus (HCMV) in vitro, with an IC₅₀ of 200 nM. It also inhibits proliferation and induces apoptosis of endometriotic stromal cells.

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