Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Arcyriaflavin A

An inhibitor of CDK4 and CaMKII
Catalog #: B2902
SKU-Size Size Price Qty
B2902-1 1 mg
$95.00
B2902-5 5 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 12,13-Dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione; 6,7,12,13-Tetrahydro-5,7-dioxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole
Appearance A crystalline solid
CAS # 118458-54-1
Molecular Formula C₂₀H₁₁N₃O₂
Molecular Weight 325.32
Purity ≥95%
Solubility ~1 mg/ml in DMSO
~5 mg/ml in DMF
SMILES C1=CC=C2C(=C1)C3=C4C(=C5C6=CC=CC=C6NC5=C3N2)C(=O)NC4=O
InChi InChI=1S/C20H11N3O2/c24-19-15-13-9-5-1-3-7-11(9)21-17(13)18-14(16(15)20(25)23-19)10-6-2-4-8-12(10)22-18/h1-8,21-22H,(H,23,24,25)
InChi Key KAJXOWFGKYKMMZ-UHFFFAOYSA-N
PubChem CID 5327723
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Arcyriaflavin A inhibits cyclin-dependent kinase 4 (CDK4) with an IC₅₀ of 140 nM. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with an IC₅₀ of 25 nM. It inhibits the replication of human cytomegalovirus (HCMV) in vitro, with an IC₅₀ of 200 nM. It also inhibits proliferation and induces apoptosis of endometriotic stromal cells.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.