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Aprotinin, Active, Bovine Recombinant (AOF)

>90% Pure Active, Bovine Recombinant, Animal Origin Free, Aprotinin. Can be used for inhibition of Trypsin and trypsin like enzymes
Catalog #: 7866
SKU-Size Size Price Qty
7866-1 1 mg
$60.00
7866-5 5 X 1 mg
$100.00
More Sizes Get Quote

Product Details

Alternate Name BPTI, Basic protease inhibitor, Pancreatic trypsin inhibitor
Gene Symbol BPI
Accession # P00974
Source E. coli
Appearance Lyophilized
Physical Form Description Lyophilized from 5 mg/ml solution in PBS
Molecular Weight 9.7 kDa (36-93 aa + N-terminal Poly-his tag)
Purity by SDS-PAGE ≥90%
Reconstitution Instructions Centrifuge the vial prior to opening at low speed. Reconstitute in water to a concentration of 1 mg/ml. The solution can then be diluted into PBS or other aqueous buffers and store at 4°C for 1 week or –20°C for future use. For long-term storage, it is re
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, Aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges. BioVision’s Recombinant Bovine Aprotinin is an animal-origin free protein purified by proprietary chromatographic techniques.


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