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Aprataxin, Human Recombinant

Play a role in single-stranded DNA repair.
Catalog #: P1575
SKU-Size Size Price Qty
P1575-10 10 μg
$135.00
P1575-50 50 μg
$625.00
More Sizes Get Quote

Product Details

Alternate Name Forkhead-associated domain histidine triad-like protein, AXA1
Gene Symbol APTX
Gene ID 54840
Accession # Q7Z2E3
Source E. coli
Appearance Liquid
Physical Form Description In 20 mM Tris-HCl buffer (pH 7.5) containing 20% glycerol, 100 mM NaCl, 0.1 mM PMSF
Molecular Weight 23.9 kDa (N-Terminal His-Tag)
Purity by SDS-PAGE >95%
Amino Acid Sequence aa 1-168
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single-stranded DNA repair. Mutations in the gene have been associated with neurological disorder known as ataxia oculomotor apraxia-1. Recombinant Aprataxin protein was expressed in E. coli and purified by using conventional chromatography techniques.


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