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Apotransferrin, Rat Plasma

Non-heme iron-transport protein.
Catalog #: 7541
$295.00

Product Details

Cat # +Size 7541-1000
Size 1 mg
Alternate Name Transferrin, TF, DKFZp781D0156, PRO1557, PRO2086
Gene Symbol TF
Gene ID 7018
Accession # P02787
Source Rat Plasma
Appearance Lyophilized
Physical Form Description Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.
Molecular Weight 80.0 kDa
Purity by SDS-PAGE ≥98%
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.


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