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Apolipoprotein AII, Human Plasma

APOA2 stabilizes the HDL structure and plays a role in its metabolism
Catalog #: 7281
$230.00

Product Details

Cat # +Size 7281-500
Size 500 μg
Alternate Name Apolipoprotein A-II, Apo-AII, ApoA-II, APOA2.
Gene Symbol ApoA2
Gene ID 336
Accession # P02652
Source Human plasma. Prepared from plasma shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Appearance Frozen
Physical Form Description Frozen in 10 mM NH4HCO3, pH 7.4
Molecular Weight 17.4 kDa
Purity by SDS-PAGE ≥ 95% by SDS - PAGE
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of Apo A in HDL is Apo AII. APOA2 is localized in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in APOA2 gene might cause apolipoprotein A-II deficiency or hypercholesterolemia. Levels of Apo AII in normal plasma range from 30-50 mg per 100 ml. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels.


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