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Product Details
| Cat # +Size | 7281-500 |
|---|---|
| Size | 500 μg |
| Alternate Name | Apolipoprotein A-II, Apo-AII, ApoA-II, APOA2. |
| Gene Symbol | ApoA2 |
| Gene ID | 336 |
| Accession # | P02652 |
| Source | Human plasma. Prepared from plasma shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. |
| Appearance | Frozen |
| Physical Form Description | Frozen in 10 mM NH4HCO3, pH 7.4 |
| Molecular Weight | 17.4 kDa |
| Purity by SDS-PAGE | ≥ 95% by SDS - PAGE |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry Ice |
| USAGE | For Research Use Only! Not to be used in humans |
Details
APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of Apo A in HDL is Apo AII. APOA2 is localized in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in APOA2 gene might cause apolipoprotein A-II deficiency or hypercholesterolemia. Levels of Apo AII in normal plasma range from 30-50 mg per 100 ml. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels.
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