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ApoC2 Antibody (Center)

Polyclonal Antibody to detect ApoC2 in human samples
Catalog #: 6718
$245.00

Product Details

Cat # +Size 6718-100
Size 100 μl
Antibody Target ApoC2
Alternate Name APOC2; APC2; Apolipoprotein C-II; Apolipoprotein C2
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen This APOC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the Central region of human APOC2.
Accession # P02655
Gene ID 344
Appearance Colorless liquid
Formulation 100 µl of antibody in PBS with 0.09% (W/V) sodium azide
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Species Reactivity Human
Application Western blot, IHC
Positive Control Western blot: HL60 and A549 cell line lysates , IHC: human liver tissue
Application & Usage Western blot: ~1:1000, IHC: ~1:10-1:50.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Apolipoproteins are plasma lipoproteins that function as transporters of lipids and cholesterol in the circulatory system. This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.


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