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Apo-SAA, human recombinant

based on 4 citations in multiple journalsApo-SAA, human recombinant44.1 4
A transient cholesterol-binding protein
Catalog #: 4324
SKU-Size Size Price Qty
4324-10 10 μg
4324-50 50 μg
4324-500 500 μg
4324-1000 1 mg
More Sizes Get Quote

Product Details

Alternate Name Serum amyloid A protein, SAA, Amyloid protein A, Amyloid fibril protein AA, Apolipoprotein, apolipoproteins, SAA1, SAA2, PIG4, TP53I4, MGC111216,
Gene Symbol SAA1
Gene ID 6288
Accession # P0DJI8
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized with no additives
Molecular Weight 11.5 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity For most in vitro applications, apo-SAA exerts its biological activity in the concentration range of 10-50 µg/ml.
Reconstitution Instructions Reconstitute in 0.1% acetic acid to a concentration of 1 μg/μl. This solution can then be diluted into other aqueous buffers.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans


Human apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 µg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apo-lipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence.

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Jacklyn G Fleischer  et al., Deactivation of the lipopolysaccharide antagonist eritoran (E5564) by high-density lipoprotein-associated apolipoproteins, Innate Immunity, Feb 2012; 18: 171 - 178.
Wilson PG et al (2008) Am. J. Pathol.; 173: 1902 - 1910.
Cai Z et al. (2007) J. Virol. 81: 6128-6133.
El Kebir D et al (2007) J. Immunol. 179: 616-622.
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