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Apg5/Atg5 Antibody

Catalog #: 3886
SKU-Size Size Price Qty
3886-30T 30 µg
$89.00
3886-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target Apg5
Alternate Name Autophagy protein 5, APG5-like , Apoptosis-specific protein, autophagy protein, atg5, atg-5, apg5, apg-5
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to residues surrounding amino acid 226 of rat Apg5
Accession # CAJ31281
Gene ID 365601
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat, pig, bovine
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~37 kDa Apg5/Atg5 from samples of human, mouse and rat origins. Reactivity to other species has not been tested.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Autophagy, the process of bulk degradation of cellular proteins throμgh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. An ubiquitin like conjμgation system is involve in the formation of autophagosome where by Atg12 is covanletly bound to Apg5/ATG5. The conjμgation is mediated by the ubiquitin-E1-like enzyme Atg7 and thE2-like enzyme Atg10.


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