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Anti-VEGF (Bevacizumab), humanized Antibody

Monoclonal human IgG1 antibody against human VEGF
Catalog #: A1045
$415.00

Product Details

Cat # +Size A1045-100
Size 100 µg
Antibody Target VEGF
Alternate Name Avastin
Host Recombinant
Antibody Type Monoclonal
Isotype Human IgG1
Immunogen Recombinant human VEGF
Accession # AAP86646
Gene ID 7422
Appearance Colourless liquid
Concentration 1 mg/ml
Formulation 100 ug of antibody in Phosphate buffered saline, pH 7.4.
Purification human IgG1 was expressed in a human cell line. IgG was purified from CHO cell culture supernatant by protein A chromatography.
Species Reactivity Human
Application Neutralization, ELISA
Application & Usage Neutralization: 0.1-20 μg/ml, ELISA: 2 μg/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Bevacizumab (Avastin) is a recombinant humanized monoclonal IgG1 antibody. Bevacizumab, targets the cell surface protein called vascular endothelial growth factor (VEGF) results in suppression of tumor growth. VEGF plays an essential role in developmental angiogenesis and is also important for reproductive and bone angiogenesis. Avastin is used to treat various cancers like metastatic colorectal cancer, non-squamous non–small cell lung cancer, metastatic breast cancer, glioblastoma and metastatic renal cell carcinoma.


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