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Anti-USP7 Antibody

Rabbit polyclonal antibody to detect USP7 expression in human, mouse and rat samples
Catalog #: A2214
$310.00

Product Details

Cat # +Size A2214-100
Size 100 µl
Antibody Target USP7
Alternate Name TEF1, HAUSP, HAFOUS, EC 3.4.19.12, EC 3.1.2.15, Ubiquitin thioesterase 7, Ubiquitin-specific-processing protease 7, Deubiquitinating enzyme 7
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Recombinant full length protein of human USP7
Accession # Q93009
Gene ID 7874
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Rat, Mouse, Human
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting
Application & Usage WB (1:500 - 1:2000), IHC (1:50 - 1:200), IF (1:50 - 1:100)
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling) and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.


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