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Anti-TNF-α, Human IgG1 Antibody (Go2)

Biosimilar to Golimumab, monoclonal antibody that targets TNF-α
Catalog #: A2141
$455.00

Product Details

Cat # +Size A2141-100
Size 100 μg
Antibody Target TNF-α
Alternate Name TNFSF2, TNF-alpha, TNFA, TNF-α, TNFα
Host Recombinant
Antibody Type Monoclonal
Isotype IgG1, kappa
Immunogen Human TNF-α
Accession # DB06674
Appearance Colorless liquid
Formulation In PBS, pH 7.5
Purification Protein A purified
Species Reactivity Human
Handling The antibody solution should be gently mixed before use.
Storage Conditions -80°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This biosimilar is a human IgG1 kappa monoclonal antibody derived from HuMab transgenic mice immunized with human tumor necrosis factor alpha (TNF-α). TNFα is a proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. TNFα is mainly secreted by macrophages and can bind to various receptors including TNFRSF1A and TNFRSF1B, thus playing a role in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNFα has been implicated in diseases such as autoimmunity and cancer.


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