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Anti-TNF alpha (Humicade), Human IgG4 Antibody

Monoclonal antibody to detect TNF alpha in human samples.
Catalog #: A1093
$625.00

Product Details

Cat # +Size A1093-200
Size 200 µg
Antibody Target TNF
Alternate Name Tumor necrosis factor superfamily member 2, TNFSF2, TNFA
Host Recombinant
Antibody Type Monoclonal
Isotype Human IgG4, kappa
Immunogen Human TNF-alpha
Accession # P01375
Gene ID 7124
Appearance Colorless liquid
Formulation 200 µg affinity purified human antibody in phosphate-buffered saline (PBS) containing 0.02% Proclin 300
Purification Affinity purified using protein A
Species Reactivity Human
Application ELISA; NTRL
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The antibody binds specifically to TNF-alpha, a pro-inflammatory cytokine which stimulates release of other cytiokines e.g. IL-1, IL-6 and GM-CSF as well as secretion of ICAM-1 and VCAM-1 from endothelial cells. It stimulates acute phase responses and acts as a chemoattractant for NK cells and monocytes/macrophages. The antibody reached Phase II clinical trials with Celltech, UCB.


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