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Anti-TNF-α (Adalimumab), humanized Antibody

Monoclonal human IgG1 antibody against human TNF-α
Catalog #: A1048
$375.00

Product Details

Cat # +Size A1048-100
Size 100 µg
Antibody Target TNF-α
Alternate Name Humira
Host Recombinant
Antibody Type Monoclonal
Isotype Human IgG1
Immunogen Recombinant human TNF a
Accession # P01375
Gene ID 7124
Appearance Colourless liquid
Formulation In Phosphate buffered saline, pH 7.4.
Purification IgG purified from CHO culture supernatant by protein A chromatography
Species Reactivity Human
Application Neutralization, ELISA
Application & Usage Neutralization : 0.01-1 μg/ml; ELISA: 1μg/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Adalimumab (Humira), a human monoclonal antibody that specifically binds to tumor necrosis factor-alpha (TNF-a). Possessing a high specificity and affinity for TNFα adalimumab exerts its therapeutic effects by blocking the interaction of TNFα with the p55 and p75 receptors as well as inducing apoptosis of TNF-expressing mononuclear cells. Adalimumab can be used for the treatment of Rhcumatoid arthritis, Juvenilc Idiopathic Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Crohn's Disease and Plaque Psoriasis.


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