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recMAb™ Anti-TIMP2 Antibody

Recombinant mouse monoclonal antibody to detect TIMP2 expression in human, mouse, rat, rabbit, guinea pig, cow and zebrafish samples
Catalog #: A2185
$355.00

Product Details

Cat # +Size A2185-100
Size 100 μg
Antibody Target TIMP2
Alternate Name DDC8, CSC-21K, Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue Inhibitor of Metalloproteinase 2
Host Mouse
Antibody Type Monoclonal
Isotype IgG1, kappa
Immunogen Synthetic peptide targeting residues around aa 40-70 at the N-terminus of human TIMP2
Accession # P16035
Gene ID 7077
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation In 10 mM PBS
Purification Protein A/G purified
Species Reactivity Human, Mouse, Rabbit, Rat, Guinea pig, Zebrafish, Bovine
Application Immunohistochemistry (IHC)
Application & Usage IHC (1-2 µg/ml)
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.


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