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Anti-TGF-b1 Antibody (3D9)

Monoclonal antibody to detect TGF-β1
Catalog #: A1338

In stock

$265.00

Product Details

Cat # +Size A1338-100
Size 100 µg
Antibody Target TGF-b1
Alternate Name Transforming growth factor beta-1, TGF-beta-1, TGFB
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1κ
Immunogen Recombinant human TGF-β1
Accession # P01137
Gene ID 7040
Appearance Colorless liquid
Formulation In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.02% sodium azide.
Purification Affinity purified
Species Reactivity Human
Application WB
Positive Control WB: HepG2 cell lysate
Application & Usage WB: 1-4 µg/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

TGF-β1 (transforming growth factor-beta) is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It also stimulates sustained production of collagen through the activation of CREB3L1 by regulated intramembrane proteolysis.


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