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New

Anti-Src (KO Validated) Antibody

Rabbit monoclonal knockout validated antibody to detect the expression of Src in human, mouse and rat samples
Catalog #: A2123
$345.00

Product Details

Cat # +Size A2123-100
Size 100 µl
Antibody Target Src
Alternate Name ASV; SRC1; THC6; c-SRC; p60-Src; SRC
Host Rabbit
Antibody Type Monoclonal
Isotype IgG
Immunogen Synthetic peptide derived from human Src
Accession # P12931
Gene ID 6714
Appearance Colorless liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purified
Species Reactivity Human, Mouse, Rat
Application Immunofluorescence (IF), Western Blotting
Application & Usage WB 1:500 - 1:2000, IF 1:50 - 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.


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