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Anti-SMARCC1 Antibody (2A4-H7-C12)

Monoclonal antibody to detect SMARCC1
Catalog #: A1315
$265.00

Product Details

Cat # +Size A1315-100
Size 100 µg
Antibody Target SMARCC1
Alternate Name BRG1-associated factor 155, BAF155, SWI/SNF complex 155 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1
Immunogen Recombinant human SMARCC1 protein fragments expressed in E.coli
Accession # Q92922
Gene ID 6599
Appearance Colorless liquid
Formulation In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol
Purification Affinity purified
Species Reactivity Human
Application WB
Positive Control WB: K562, Jurkat and HeLa cell lysates
Application & Usage WB; 1:1000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.


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