Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

New

Anti-SARS-CoV-2 S2 Antibody (Clone# AbH722)

Recombinant monoclonal antibody (Clone# AbH722) to detect the expression of SARS-CoV-2 Spike S2 protein
Catalog #: A2268
$480.00

Product Details

Cat # +Size A2268-100
Size 100 μg
Antibody Target SARS-CoV-2 Spike S2
Alternate Name Spike protein, COVID19, COVID 19, S protein, SARS-CoV S protein, S glycoprotein, E2, Peplomer protein, Spike protein S1, SARS Coronavirus, SARS-CoV-2, SARS CoV 2, 2019-nCoV, Spike protein S2, S2 protein, AbH722
Host Recombinant
Antibody Type Monoclonal
Isotype Human IgG
Immunogen Recombinant SARS-CoV-2 S2 protein
Appearance Colorless liquid
Formulation In PBS, pH 7.5
Species Reactivity Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV
Handling The antibody solution should be gently mixed before use.
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The Spike protein (S) is a type I membrane fusion protein required for viral infection and pathogenesis. It is synthesized as a precursor protein between 1200 to 1300 amino acids. The mature protein is a heavily glycosylated trimer with 21-35 glycosylation sites. Upon cleavage by host proteases, it yields 2 subunits, S1 and S2. The S1 subunit consists of 672 amino acids and is divided into 4 domains: an N-terminal domain, a C-terminal domain (also called receptor binding domain, RBD), and 2 subdomains SD1 and SD2. The S2 subunit consists of 588 amino acids and is divided into 4 domains: an N-terminal hydrophobic fusion peptide (FP), 2 heptad repeats (HR1 and HR2), a transmembrane domain (TM), and a cytoplasmic tail. When S1 recognizes and binds to the host receptor, the S2 subunit undergoes a conformational change to bring about the fusion of viral envelope and host cell membrane. Current strategies involve the development of anti-viral drugs to inhibit infection of coronavirus.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.