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Anti-RPS6 Antibody

Affinity purified rabbit polyclonal antibody to detect Ribosomal Protein S6 expression in human, mouse, rat, bovine, chicken, dog, monkey and rabbit samples
Catalog #: A1995
$320.00

Product Details

Size 100 µl
Antibody Target Ribosomal Protein S6
Alternate Name 40S ribosomal protein S6; Phosphoprotein NP33
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human RPS6
Accession # P62753
Gene ID 6194
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Dog, Rabbit, Bovine, Human, Rat, Chicken, Mouse, Monkey
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting
Application & Usage WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.


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