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Anti-PSMA (Prostate specific membrane antigen) Rabbit Monoclonal Antibody (RM327)

Affinity purified Rabbit monoclonal to PSMA (Prostate specific membrane antigen)
Catalog #: A1841
$240.00

Product Details

Cat # +Size A1841-50
Size 50 µl
Antibody Target PSMA (Prostate specific membrane antigen)
Host Rabbit
Antibody Type Monoclonal
Isotype Rabbit IgG
Immunogen A peptide corresponding to the C-terminus of human PSMA (Prostate-specific membrane antigen).
Accession # Q04609
Gene ID 2346
Appearance Liquid
Formulation 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification Protein A affinity purified from an animal origin–free culture supernatant
Species Reactivity Human
Application Immunohistochemistry (IHC), Western Blotting
Application & Usage IHC: 1:500-1:1000, Western Blot: 1:1000-1:2000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Human Prostate Specific Membrane Antigen (PSMA), a tumor marker in prostate cancer encoded by FOLH1 gene, is a surface glycoprotein with high expression in prostate epithelium. PSMA expression level increases in primary and metastatic prostate cancer and the neovasculature of nonprostatic epithelial malignancies. Overexpression of PSMA is correlated with high tumor grade, non-diploid tumors, and advanced tumor stage. PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It is also recognized as a viable target for cancer therapy.


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