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New

Anti-PSA, Rabbit Monoclonal Antibody (RM323)

Affinity purified Rabbit monoclonal to PSA (Prostate Specific Antigen)
Catalog #: A1847
$240.00

Product Details

Cat # +Size A1847-50
Size 50 µl
Antibody Target PSA (Prostate Specific Antigen)
Host Rabbit
Antibody Type Monoclonal
Isotype Rabbit IgG
Immunogen Native PSA protein purified from human seminal fluid.
Accession # P07288
Gene ID 354
Appearance Liquid
Formulation 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification Protein A affinity purified from an animal origin–free culture supernatant
Species Reactivity Human
Application Immunohistochemistry (IHC), Western Blotting, ELISA
Application & Usage Western Blot (WB-Non-Reduced): 1:1000-1:2500, IHC: 1:500-1:1000, ELISA: 1:1000-1:5000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Prostate-specific antigen (PSA) is also known as kallikrein III, seminin, semenogelase, γ-seminoprotein and P-30 antigen. It is a serine protease enzyme produced by the cells of the prostate gland. Most of PSA in the blood which is bound to serum proteins is known as total PSA, while a small amount which is not protein bound to is called free PSA. PSA liquifies the semen in the seminal coagulum and allows sperm to swim freely. PSA is often elevated in the presence of prostate cancer and in other prostate disorders. A blood test to measure PSA is considered to be the most effective test currently available for the early detection of prostate cancer. Furthermore, rising levels of PSA over time are associated with both localized and metastatic prostate cancer (CaP). Human PSA monoclonal antibody, is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with human total PSA purified from semenal plasma.


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