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Anti-PPAR gamma Antibody

Polyclonal antibody to detect endogenous levels of PPAR gamma in human samples
Catalog #: A1712

In stock

SKU-Size Size Price Qty
A1712-30T 30 µg
$89.00
A1712-100 100 µg
$265.00
More Sizes Get Quote

Product Details

Antibody Target PPAR gamma
Alternate Name PPAR-gamma, Peroxisome Proliferator-activated Receptor γ Ligand Binding Domain, PPAR-gamma (LBD), NR1C3, PPARG (LBD)
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # P37231
Gene ID 5468
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In PBS pH7.2 with 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human
Application Western Blotting
Positive Control Human recombinant PPAR gamma
Application & Usage Western blot: 1-4 µg
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The peroxisome proliferator activated receptor (PPAR) family of ligand activated transcription factors consists of three subtypes encoded by separate genes: PPARα, PPARδ and PPARγ. Of these, PPARγ plays an important role in the regulation of fatty acid storage and glucose metabolism. The genes activated by PPARγ stimulate lipid uptake and adipogenesis by fat cells. Many naturally occurring molecules such as, polyunsaturated fatty acids like arachidonic acid and arachidonic acid metabolites, are known to bind and activate PPARγ. The binding of activating ligands to the ligand binding domain (LBD) of PPARγ promotes its heterodimerization with retinoic acid-like receptor (RXR), which results in the regulated expression of target genes involved in lipid metabolism.


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