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Anti-PON1 Antibody (Clone# ARC2001)

Affinity purified rabbit monoclonal antibody to detect the expression of PON1 in human, mouse and rat samples
Catalog #: A2229
$365.00

Product Details

Cat # +Size A2229-100
Size 100 μl
Antibody Target PON1
Alternate Name Paraoxonase 1, PON 1, K-45, ESA, PON, EC 3.1.1.81, EC 3.1.1.2, EC 3.1.8.1, MVCD5, PON1
Host Rabbit
Antibody Type Monoclonal
Isotype IgG
Immunogen Synthetic peptide derived from human PON1
Accession # P27169
Gene ID 5444
Appearance Colorless liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purified
Species Reactivity Rat, Mouse, Human
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting
Application & Usage WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high-density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7.


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