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Anti-Phospho-AKT1 (Y315) / AKT2 (Y316) / AKT3 (Y312) Polyclonal Antibody

A family of oncogenes that acts as critical factors in signaling pathways
Catalog #: A2347
SKU-Size Size Price Qty
A2347-50 50 µl
$195.00
A2347-100 100 µl
$345.00
More Sizes Get Quote

Product Details

Antibody Target Human AKT1 / AKT2 / AKT3 phosphorylated at Y315 / Y316 / Y312
Alternate Name PKB; Protein Kinase B; Protein Kinase B Beta; Protein Kinase B Gamma
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen A phospho specific peptide corresponding to residues surrounding Y315 of human AKT1
Accession # P31749 (AKT1); P31751 (AKT2); Q9Y243 (AKT3)
Gene ID 207 (AKT1); 208 (AKT2); 10000 (AKT3)
Appearance Liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purification
Species Reactivity Human
Application Western Blotting
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The human AKT serine-threonine kinase family consists of three members (AKT1, AKT2, and AKT3) that are phosphorylated by phosphoinositide 3-kinase (PI3K) upon activation of cell membrane-associated signaling molecules such as receptor tyrosine kinases. AKT proteins regulate a wide variety of cellular functions including cell proliferation, survival, metabolism, and angiogenesis. Mutations in AKT are associated with multiple forms of cancer and hyperplasia.


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