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Anti-PEG10 Antibody (1E2-F12-C12)

Monoclonal antibody to detect PEG10
Catalog #: A1321
$265.00

Product Details

Cat # +Size A1321-100
Size 100 µg
Antibody Target PEG10
Alternate Name Retrotransposon-derived protein PEG10, Embryonal carcinoma differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1
Immunogen Recombinant human PEG10 protein fragments expressed in E.coli
Accession # Q86TG7
Gene ID 23089
Appearance Colorless liquid
Formulation In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Purification Affinity purified
Species Reactivity Human
Application WB, IP
Positive Control WB; HeLa cell lysate, IP: HeLa cell lysate
Application & Usage WB; 1:1000, IP
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter.


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