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Anti- PEG Antibody (Clone 26A04)

Anti-PEG Monoclonal Antibody (Clone 26A04)
Catalog #: 5019
$245.00

Product Details

Cat # +Size 5019-100
Size 100 µg
Antibody Target PEG
Alternate Name Polyethylene Glycol
Host Rat
Antibody Type Monoclonal
Isotype IgM
Immunogen PEG-KLH
Accession # N/A
Gene ID N/A
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation 1 mg/ml in TBS, pH 9.0
Purification Ceramic hydroxyapatite (CHT) chromatography from in vitro production
Species Reactivity All. It reacts with PEGylated proteins such as PEG-GCSF, PEG-Erythropoietin, and PEG-Interferon, but does not react to unmodified form of the same proteins.
Application ELISA, WB, Serves as Positive Controls for Drμg Detection Assays.
Positive Control 3 PEG Conjμgates (20 kDa, 5 kDa, 10 kDa)
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Polyethylene Glycol (PEG) is a polymer of ethylene oxide available in size variants from 400 Da to 40 kDa. It is nonionic, nontoxic, biocompatible, strong, and hydrophilic and has a large exclusion volume in aqueous solution. PEG has a number of industrial and biomedical applications. The modification of a biopharmaceutical with PEG increases its hydrodynamic radius, reduces immunogenicity and proteolytic cleavage. In particular, therapeutic proteins are conjμgated with PEG to slow down their clearance from circulation and improve bioavailability. PEG antibodies can be a vital tool for propelling therapeutics to market by serving as a positive control anti-drμg antibody, measuring clearance of a drμg, or simply as a QA release confirming PEGylation.


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