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Anti-PD-L1, Human IgG1 Antibody (Dv3)

Biosimilar to Durvalumab, monoclonal antibody that targets PD-L1
Catalog #: A2109
$455.00

Product Details

Cat # +Size A2109-100
Size 100 μg
Antibody Target PD-L1
Alternate Name PDL1, PD-L1, PD L1, B7-H, B7H1, B7-H1, CD274, PDCD1L1, B7 homolog 1, PDCD1 ligand 1, programmed cell death 1 ligand 1, Programmed death ligand 1
Host CHO cells
Antibody Type Monoclonal
Isotype Human IgG1, kappa
Immunogen Human PD-L1
Accession # DB11714
Appearance Colorless liquid
Formulation In PBS buffer, pH 7.2
Application HTRF assay
Application & Usage HTRF assay
Handling The antibody solution should be gently mixed before use.
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The research-grade biosimilar is a human IgG1 monoclonal antibody that is produced by recombinant DNA technology in CHO cells to target programmed cell death-ligand 1 (PD-L1). PD-L1 is an immune inhibitory receptor ligand that is expressed by T and B lymphocytes, as well as various types of tumor cells to escape immune surveillance. Binding of PDL1 to the PD-1 and B7.1 receptors occurs on T cells and antigen-presenting cells that results in suppression of cytotoxic T-cell activity, T-cell proliferation, and cytokine production. During infection or inflammation, PD-L1 plays a role in preventing autoimmunity by maintaining homeostasis of the immune response.


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