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Anti-PD-L1 Humanized Antibody (Atz)

Biosimilar to Atezolizumab, monoclonal antibody that targets PD-L1
Catalog #: A1305
$425.00

Product Details

Cat # +Size A1305-100
Size 100 µg
Antibody Target PD-L1
Alternate Name CD274, Programmed Cell Death 1 Ligand 1, B7H1
Antibody Type Monoclonal
Isotype Human IgG1
Immunogen Human programmed cell death 1 ligand 1 (PD-L1)
Accession # Q9NZQ7
Gene ID 29126
Appearance Colorless liquid
Formulation Supplied in phosphate buffered saline, pH 7.2
Species Reactivity Human
Handling The antibody solution should be gently mixed before use
Storage Conditions Store the undiluted solution at 4 °C in the dark. Avoid repeated freeze-thaw cycles
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This research-grade biosimilar is a fully-humanized, engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). PD-L1 is an immune inhibitory receptor ligand that is expressed by T and B lymphocytes, as well as various types of tumor cells to escape immune surveillance. Interactions between PD-L1 and its receptor, PD-1, inhibits T cell activation and cytokine production. During infection or inflammation, PD-L1 plays a role in preventing autoimmunity by maintaining homeostasis of the immune response.


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