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Anti-PD-1, Humanized Antibody (St6)

Biosimilar to Spartalizumab, monoclonal antibody that targets PD-1
Catalog #: A2131

Product Details

Cat # +Size A2131-100
Size 100 µg
Antibody Target PD-1
Alternate Name PDCD1, PD1, CD279, SLEB2, hPD-1, hPD-l
Host CHO cells
Antibody Type Monoclonal
Isotype Human IgG4
Immunogen Human PD-1
Appearance Colorless liquid
Formulation In PBS buffer, pH 7.2
Application In vivo studies
Application & Usage In vivo studies
Handling The antibody solution should be gently mixed before use.
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The research-grade biosimilar is a humanized IgG4 monoclonal antibody that targets programmed death-1 (PD-1), a transmembrane protein belonging to the immunoglobulin (Ig) superfamily. PD-1 is an important immune checkpoint protein expressed on activated T-cells, B-cells, and macrophages. PD-1 is involved in the regulation of T cell functions, including those of effector CD8-positive T cells. PD-1 can also promote the differentiation of CD4-positive T cells into T regulatory cells, and is involved in safeguarding against autoimmunity. Binding of PD-1 to its ligands PD-L1 and PD-L2 prevent T-cell activation and cytokine production. PD-1 is expressed in many types of tumors including melanomas, and has been shown to play a role in anti-tumor immunity.

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