Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Anti-PD-1, Humanized Antibody (Nv7)

Biosimilar to Nivolumab, monoclonal antibody that targets PD-1
Catalog #: A1307
$435.00

Product Details

Cat # +Size A1307-100
Size 100 µg
Antibody Target PD-1
Alternate Name Programmed Cell Death 1; CD279; SLEB2; HPD-L; PDCD1
Antibody Type Monoclonal
Isotype Human IgG4
Immunogen Human programmed cell death 1 receptor (PD1)
Accession # Q15116
Gene ID 5133
Appearance Colorless liquid
Formulation Supplied in phosphate buffered saline, pH 7.2
Species Reactivity Human
Handling The antibody solution should be gently mixed before use
Storage Conditions Store the undiluted solution at 4 °C in the dark. Avoid repeated freeze-thaw cycles
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PD-1 is an important immune checkpoint protein expressed on activated T-cells, B-cells, and macrophages. PD-1 is involved in the regulation of T cell functions, including those of effector CD8- positive T cells. PD-1 can also promote the differentiation of CD4- positive T cells into T regulatory cells, and is involved in safeguarding against autoimmunity. Binding of PD-1 to its ligands PD-L1 and PD-L2 prevent T-cell activation and cytokine production. PD-1 is expressed in many types of tumors including melanomas, and has been shown to play a role in anti-tumor immunity.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.