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Anti-PCSK9, Human IgG2 Antibody (Ev2)

Biosimilar to Evolocumab, monoclonal antibody that targets PCSK9
Catalog #: A2168
$455.00

Product Details

Cat # +Size A2168-100
Size 100 μg
Antibody Target PCSK9
Alternate Name FH3, PC9, FHCL3, NARC1, LDLCQ1, NARC-1, HCHOLA3
Host Recombinant
Antibody Type Monoclonal
Isotype IgG2, lambda
Immunogen Human PCSK9
Accession # DB09303
Appearance Colorless liquid
Formulation In PBS, pH 7.5
Purification Protein A purified
Species Reactivity Human
Handling The antibody solution should be gently mixed before use.
Storage Conditions -80°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The research-grade biosimilar is a human IgG2 monoclonal antibody that is directed against proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a serine protease that binds to LDL receptors on the hepatocyte cell surface and promotes the lysosome-mediated degradation of these receptors. This results in decreased uptake and clearance of LDL-C (bad cholesterol) by the receptors. PCSK9 is secreted by the liver and plays a role in cholesterol and fatty acid metabolism.


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