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Anti-p53 Antibody (56F12-2)

Monoclonal Antibody to detect p53 in human, mouse and rat samples
Catalog #: A1581
$395.00

Product Details

Cat # +Size A1581-100
Size 100 µg
Antibody Target p53
Alternate Name BCC7; Cellular tumor antigen p53; FLJ92943; LFS1; Mutant tumor protein 53; p53; p53 tumor suppressor; P53_HUMAN; Phosphoprotein p53; Tp53; Transformation related protein 53; TRP53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53
Host Mouse
Antibody Type Monoclonal
Isotype Mouse / IgG1
Immunogen Purified recombinant fragment of human p53 expressed in E. coli
Accession # P04637
Gene ID 7157
Appearance Colorless liquid
Formulation In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Purification Affinity purified
Species Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ELISA
Positive Control WB: HEK293 cells, IHC: esophagal and ling cancer tissue
Application & Usage ELISA 1:10000, WB 1:500 – 1:2000, IHC 1:200 – 1:1000 , IF 1:200, ELISA (peptide) 1:20000-1:40000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

p53 also known as tumor protein 53 or TP53. It is a tumor suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumors, including those of the breast, ovarian, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma.


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