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Anti-p38 MAPK Rabbit Monoclonal Antibody

Rabbit monoclonal antibody to detect p38 MAPK in human samples.
Catalog #: A1125
$295.00

Product Details

Cat # +Size A1125-50
Size 50 µl
Antibody Target MAPK14
Alternate Name Mitogen-activated protein kinase 14, MK14, Mapk14, Mitogen-activated protein kinase p38alpha, MAP kinase p38alpha, CRK1, Csbp1, Csbp2, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX--interacting protein 2, MAP kinase MXI2, SAPK2A
Host Rabbit
Antibody Type Monoclonal
Isotype Rabbit IgG
Immunogen A peptide corresponding to human p38 MAPK.
Accession # Q16539 , Q15759 , P53778
Gene ID 1432 , 5600 , 6300
Appearance Colorless liquid
Formulation In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification Affinity purified using protein A
Species Reactivity Human
Application IHC, WB
Positive Control WB: human breast cancer tissue; IHC: HeLa cell lysates
Application & Usage IHC: 1:1000 -1:5000 dilution;WB: 1:1000 - 1:2000 dilution.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

p38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cell cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including inflammatory cytokines, UV light and growth factors, etc. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.


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