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Product Details
| Cat # +Size | A1125-50 |
|---|---|
| Size | 50 µl |
| Antibody Target | MAPK14 |
| Alternate Name | Mitogen-activated protein kinase 14, MK14, Mapk14, Mitogen-activated protein kinase p38alpha, MAP kinase p38alpha, CRK1, Csbp1, Csbp2, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX--interacting protein 2, MAP kinase MXI2, SAPK2A |
| Host | Rabbit |
| Antibody Type | Monoclonal |
| Isotype | Rabbit IgG |
| Immunogen | A peptide corresponding to human p38 MAPK. |
| Accession # | Q16539 , Q15759 , P53778 |
| Gene ID | 1432 , 5600 , 6300 |
| Appearance | Colorless liquid |
| Formulation | In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Purification | Affinity purified using protein A |
| Species Reactivity | Human |
| Application | IHC, WB |
| Positive Control | WB: human breast cancer tissue; IHC: HeLa cell lysates |
| Application & Usage | IHC: 1:1000 -1:5000 dilution;WB: 1:1000 - 1:2000 dilution. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
p38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cell cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including inflammatory cytokines, UV light and growth factors, etc. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.
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