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Anti-P-Glycoprotein Polyclonal Antibody

Involved in translocation of drugs and phospholipids across cellular membranes
Catalog #: A2377
SKU-Size Size Price Qty
A2377-50 50 µl
A2377-100 100 µl
More Sizes Get Quote

Product Details

Antibody Target Human P-glycoprotein
Alternate Name ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1; ABCB1Human P-glycoprotein
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen A synthetic peptide corresponding to a sequence within amino acids 600-700 of human P Glycoprotein
Accession # P08183
Gene ID 5243
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purification
Species Reactivity Mouse, Human
Application Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The P-glycoprotein (ABCB1) is a membrane-associated protein that transports drugs and phospholipids across cellular membranes. P-glycoprotein is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity and is involved in multidrug resistance. Disruptions in this gene are associated with colchicine resistance and inflammatory bowel disease, and may result in development of resistance to anticancer drugs.

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