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Anti-NS1 of Dengue Virus, Humanized Antibody

A humanized monoclonal antibody that targets Dengue virus NS1 protein
Catalog #: A2297
SKU-Size Size Price Qty
A2297-50 50 µg
$295.00
A2297-100 100 µg
$425.00
More Sizes Get Quote

Product Details

Antibody Target NS1 protein portion of Dengue virus genome polyprotein
Alternate Name Non-structural protein 1
Host CHO cells
Antibody Type Monoclonal
Isotype IgG1
Accession # Q99D35
Gene ID 5075727
Appearance Liquid
Formulation In PBS, pH 7.5
Species Reactivity Dengue virus
Handling The antibody solution should be gently mixed before use.
Storage Conditions Store at -80 °C. Avoid repeated freeze-thaw cycles.
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The mosquito-borne Dengue viruses (serotype 1-4) cause dengue fever, a severe flu-like illness. The disease is prevalent in Third World tropical regions, and continues to spread to sub-tropical developed countries, as well the United States. The Dengue viral genome consists of a single-stranded RNA that encodes a single polyprotein. The Dengue genome polyprotein, upon translation, is then co- and post-translationally cleaved into 11 mature proteins, including the non-structural protein NS1. Dengue NS1 has been implicated in the viral immune evasion ability by antagonizing complement function as well as inhibiting Toll-like receptor 3 signal transduction. This research-grade biosimilar is a humanized antibody that targets the Dengue NS1 protein.


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