Product Details
| Cat # +Size | A1764-100 |
|---|---|
| Size | 100 µl |
| Antibody Target | NF-kappa-B inhibitor delta |
| Alternate Name | I-kappa-B-delta, IkappaBNS, IKBD, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor delta, TA-NFKBH |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | IgG |
| Accession # | Q8NI38 |
| Gene ID | 84807 |
| Appearance | Colorless liquid |
| Concentration | 0.3 mg/ml |
| Formulation | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Purification | Affinity purification |
| Species Reactivity | Human |
| Application | Immunohistochemistry (IHC), Western Blotting, ELISA |
| Application & Usage | WB 1:500-1:2000, IHC 1:25-1:100 |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.
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