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Anti-LITAF (KO validated) Antibody

Rabbit polyclonal knockout validated antibody to detect the expression of LITAF in human, mouse and rat samples
Catalog #: A2075
$345.00

Product Details

Cat # +Size A2075-100
Size 100 μl
Antibody Target LITAF
Alternate Name LITAF; PIG7; SIMPLE; TP53I7
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Recombinant fusion protein targeting a sequence around aa 1-161 of human LITAF
Accession # Q99732
Gene ID 9516
Appearance Colorless liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purified
Species Reactivity Mouse, Rat, Human
Application Western Blotting, Immunohistochemistry (IHC)
Application & Usage WB 1:500 - 1:2000, IHC 1:50 - 1:200, IP 1:50 - 1:100
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.


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