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Anti-KRT8 recMAb™ Antibody

Recombinant rabbit monoclonal antibody to detect the expression of KRT8 in human samples
Catalog #: A2197
$375.00

Product Details

Cat # +Size A2197-100
Size 100 μg
Antibody Target KRT8
Alternate Name K8, KO, CK8, CK-8, CYK8, K2C8, CARD2
Host Rabbit
Antibody Type Monoclonal
Isotype IgG
Immunogen Recombinant human KRT8 protein fragment (aa 343-357)
Accession # P05787
Gene ID 3856
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation In 10 mM PBS
Purification Protein A/G purified
Species Reactivity Human
Application Immunohistochemistry (IHC), Western Blotting
Application & Usage WB (1-2 µg/ml), IHC (1-2 µg/ml)
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.


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