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Anti-KLF4 Antibody

Polyclonal antibody to detect endogenous levels of KLF4 in human, mouse and rat sample
Catalog #: A1684

In stock

$295.00

Product Details

Cat # +Size A1684-100
Size 100 µl
Antibody Target KLF4
Alternate Name EZF; GKLF; Krueppel-like factor 4; Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Recombinant full length protein of human KLF4
Accession # O43474
Gene ID 9314
Appearance Liquid
Concentration 1 mg/ml
Formulation In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.
Purification Affinity purification
Species Reactivity Rat,Mouse,Human
Application Immunohistochemistry (IHC),Western Blotting
Application & Usage IHC; 1:50 - 1:100,WB; 1:500 - 1:2000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.


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