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Anti-Junctional Adhesion Molecule 1 Rabbit Monoclonal Antibody

Monoclonal antibody to detect JAM1 in human samples.
Catalog #: A1596

In stock

$285.00

Product Details

Cat # +Size A1596-50
Size 50 µl
Antibody Target Junctional Adhesion Molecule 1
Alternate Name Junctional adhesion molecule 1, JAM-1, JCAM, F11R, CD321
Host Rabbit
Antibody Type Monoclonal
Isotype Rabbit IgG
Immunogen A peptide corresponding to the N-terminus of human human JAM1 (Junctional adhesion molecule 1)
Accession # Q9Y624
Gene ID 50848
Appearance Colorless liquid
Formulation In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification Affinity purified
Species Reactivity Human
Application WB, IHC
Positive Control WB: HEK293 cells lysates, IHC: Kidney tissue sections
Application & Usage WB: 1:250-1:1000, IHC: 1:2000-1:10000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation.


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