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Anti-ITGA6 Antibody

Polyclonal antibody to detect endogenous levels of ITGA6 in human and mouse sample
Catalog #: A1681

In stock

$395.00

Product Details

Cat # +Size A1681-100
Size 100 µl
Antibody Target ITGA6
Alternate Name Alpha6p; CD49 antigen-like family member F; CD49f; Integrin alpha6B; Integrin, alpha 6; ITA6_HUMAN; ITGA6; ITGA6B; Processed integrin alpha-6; VLA 6; VLA-6
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen A synthesized peptide derived from human ITGA6
Accession # P23229
Gene ID 3655
Appearance Liquid
Concentration 1 mg/ml
Formulation In phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C
Purification Affinity purified
Species Reactivity Mouse,Human
Application Immunohistochemistry (IHC),Western Blotting,ELISA
Application & Usage ELISA (peptide) 1:20000-1:40000,IHC 1:200,WB 1:1000-3000 IHC 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.


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